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Hair Mesotherapy in Izmir

Hair is the most complementary element of physical appearance for both women and men. However, factors such as genetic predisposition, hormonal changes, stress, inadequate nutrition, environmental pollution, and seasonal changes can cause hair follicles (roots) to weaken and fall out. Hair loss (alopecia) is not only an aesthetic concern but can also be a sign of some deficiencies in the body’s metabolic balance. In modern dermatology, one of the most effective minimally invasive methods used to stop hair loss and strengthen existing hair is “Hair Mesotherapy”. As Izmir Private Demiderm Polyclinic, we approach your hair health with a holistic medical perspective, applying scientific protocols that deliver the building blocks that hair follicles need directly to the target tissue. In this comprehensive guide, we will examine all the details of hair mesotherapy, from its mechanism of action and content analysis to the application process and its differences from PRP, in light of scientific data.

What is Hair Mesotherapy?

Hair mesotherapy is a procedure in which a special cocktail of vitamins, minerals, amino acids, enzymes, and growth factors, necessary for hair growth, development, and vitality, is prepared and injected into the middle layer of the scalp (dermis) with micro-needles. This method is an adaptation of the mesotherapy technique developed by Dr. Michel Pistor in 1952 to the field of trichology (hair science).

Oral supplements or topical shampoos/lotions can lose a large part of their effectiveness by being absorbed in the systemic circulation or skin barrier before reaching the hair follicles. The basic philosophy of hair mesotherapy is the principle of “applying treatment where the problem is.” In this way, nutrients are delivered directly to the vascular network (capillary system) that nourishes the hair follicles, ensuring maximum bioavailability.

How Does Hair Mesotherapy Work?

The effect of mesotherapy is based on two main mechanisms:

Pharmacological Effect: The active substances in the injected mixture accelerate the metabolism of the hair follicle. For example, B vitamins increase hair strand production, while minerals such as copper and zinc help slow down hormonally induced hair loss (DHT suppressive effect).
Physical Effect (Micro-Trauma): The needling process creates controlled and microscopic damage to the scalp. To repair this micro-damage, the body sends growth factors to the area and increases blood flow (angiogenesis). Increased blood circulation allows hair follicles to receive more oxygen and nutrients.What Problems Does Hair Mesotherapy Solve?
Hair mesotherapy can be used as a supportive or primary treatment in a wide range of indications:

Androgenetic Alopecia (Male Pattern Hair Loss): Slowing down genetic hair loss and thickening miniaturized (feathery) hair.
Telogen Effluvium (Disseminated Hair Loss): Sudden hair loss due to stress, post-pregnancy, seasonal changes, or nutritional deficiencies. Alopecia Areata (Hair Loss): To accelerate hair growth after the active phase of the disease has passed. Loss of Hair Quality: Broken, dull, thinning, and volumeless hair.
Seborrheic Dermatitis and Dandruff: Controlling dandruff and oiliness problems by regulating the moisture balance of the scalp.
Slow Growth: Situations where hair growth has stopped or slowed down.

Application Process and Treatment Stages

At Izmir Private Demiderm Polyclinic, hair mesotherapy is performed in the following steps, strictly adhering to sterilization rules:

1. Analysis and Examination: Before the procedure, the scalp is examined with a dermatoscope. The type of hair loss, hair thickness, and follicle density are analyzed. A mesotherapy cocktail is prepared according to the patient’s needs.

2. Preparation and Disinfection: The area to be treated is cleaned with antiseptic solutions. Topical anesthetic sprays can be used for patients with a low pain threshold.

3. Injection: Using very fine-tipped (30G or 32G) mesotherapy needles or a special mesotherapy gun, the prepared cocktail is injected in small doses into the hair follicles at a depth of 2-4 mm.

4. Massage and Finishing: After the procedure, a special massage is performed on the scalp to ensure homogeneous distribution of the medication. The procedure takes approximately 15-20 minutes. Who is Hair Mesotherapy Suitable For?

Hair mesotherapy is suitable for women and men who are experiencing hair loss or who want to improve hair quality and who are in good general health. However, it is not applied in some cases (contraindications):

Pregnant and breastfeeding women (first 6 months).
Cancer treatmentPatients undergoing treatment (Oncologist approval required).

Those taking blood thinners or those with clotting disorders.
Those with active infection or open wounds in the application area.
Those allergic to any of the ingredients in the mixture.

Vitamins and Minerals Used in Hair Mesotherapy

The success of the treatment depends on the richness of the prepared cocktail. Commonly used components include:

B Vitamins (Biotin, B5, B6, B12): Supports keratin production, strengthens hair structure, and helps prevent hair loss.
Amino Acids (Cysteine, Methionine, Arginine): Necessary for the synthesis of proteins, the basic building blocks of hair.
Minerals (Zinc, Copper, Magnesium): Regulates enzymatic reactions and may suppress the 5-alpha reductase enzyme (which causes hair loss).
Hyaluronic Acid: Maintains the moisture balance of the scalp and improves the area around the follicle.
Coenzyme Q10 and Antioxidants: Reduces oxidative stress, thus delaying the aging of hair follicles.
Vasodilators (Vascular Dilators): They increase blood flow, thus nourishing the hair follicles.

How Many Sessions of Hair Mesotherapy Are Needed?

Mesotherapy is a treatment that shows a cumulative effect. It is not correct to expect miracles in a single session. The number of sessions varies depending on the severity and type of hair loss, but the general protocols are as follows:

Initial Treatment: Usually planned between 6 and 10 sessions.
For Acute Hair Loss: Application is done once a week.
For Chronic and Slow Hair Loss: Application can be done every 15 days.
Maintenance Treatment: After the completion of the treatment, single-session booster doses are recommended once a month or every 3 months to maintain the result.

Session Intervals and Treatment Duration

The ideal session interval is determined according to the hair follicles’ response to the medication. Generally, the first 4 sessions are applied weekly, and the next 4 sessions are applied every 15 days. The total treatment process can take approximately 3-4 months. Patience and consistency are the most important factors for the success of the treatment.

Effectiveness of Mesotherapy for Hair Loss

Clinical observations and studies show that mesotherapy is quite effective, especially in the early stages of hair loss and in thickening thinning hair. It does not have the ability to grow new hair in areas where hair has completely fallen out and the follicle has closed (bald); however, it can increase hair density by awakening existing, weakened and “dormant” roots.

Strengthening Hair Roots with Mesotherapy

Weak hair roots go into the shedding phase without completing the “Anagen” phase, which is the hair growth phase. Mesotherapy prolongs the anagen phase, allowing the hair to stay on the head longer. It also thickens the diameter of the hair, creating an increase in volume. In this way, the hair looks fuller and thicker.

Things to Consider After Hair Mesotherapy

Hair should not be washed for at least 24 hours after the procedure.
Hair styling products (gel, spray, etc.) should not be used for the first 24 hours.
Sweating activities such as Turkish baths, saunas, swimming pools, and strenuous sports should be avoided on the day of the procedure.
The application area should not be touched with hands; hygiene should be observed to prevent the risk of infection.
A hat can be worn to protect against the sun’s rays.

Post-Procedure Recovery Process

Mesotherapy is a “lunchtime” procedure that does not affect social life. After the procedure, there may be slight redness, minimal swelling, or small bruises on the scalp. These effects usually disappear spontaneously within a few hours or at most within 1-2 days. The patient can return to their daily life immediately after the procedure.

Comparison of Hair Mesotherapy and PRP

PRP (Platelet Rich Plasma) and Mesotherapy are two methods that are often confused in hair treatment but work with different mechanisms.

Features	Hair Mesotherapy	PRP (Platelet-Rich Plasma)
Contents	Ready-made cocktail of vitamins, minerals, and medications.	Growth factors obtained from the patient’s own blood.
Source	External (Synthetic/Natural) components.	Autologous (The person’s own blood).
Purpose	To replace deficiencies and nourish.	Cell Renewal and repair.
Application Frequency	More frequently (Weekly).	Less frequently (Every 2-3 weeks).
Combination	Can be done together with PRP.	Can be done together with Mesotherapy.

Hair Mesotherapy Applications in Women and Men

In men, hair loss is usually genetic (androgenic).Iron deficiency is prominent, and mesotherapy cocktails may contain DHT-suppressing agents for this purpose. In women, hair loss is common due to iron deficiency, thyroid problems, or hormonal changes. Therefore, cocktails used in women are more nourishing and improve circulation.

The Effect of Mesotherapy on Seasonal Hair Loss

Hair loss that increases especially in autumn and spring (seasonal hair loss) is related to the hair follicles entering a resting phase. Mesotherapy acts as a protective shield during these periods. A short course (3-4 sessions) started before seasonal changes minimizes hair loss and allows the hair to get through this process without damage.

Is There Pain During Hair Mesotherapy?

Mesotherapy needles are extremely thin (even thinner than an insulin needle). Patients usually feel a slight stinging or prickling sensation during the procedure. This sensation is not unbearable pain. In individuals with a very low pain threshold, comfort can be increased by applying a local anesthetic spray or cream before the procedure.

Use of Mesotherapy in Post-Pregnancy Hair Loss

Intense hair loss, known as “Postpartum Alopecia,” which begins approximately 3-4 months after childbirth, can be worrying for mothers. This is part of the hormonal balancing process. After the breastfeeding period ends, or with doctor’s approval, mesotherapy is very effective in stopping this hair loss and restoring the hair’s former thickness.

When Does Hair Mesotherapy Show Effects?

It is expected that hair loss will stop or significantly decrease in the first 2-3 sessions. Improvement in hair quality, shine, and volume usually becomes noticeable after the 4th-5th session. New hair growth (baby hairs) is observed towards the end of the treatment or in the months following the completion of the treatment.

The Permanence and Sustainability of Hair Mesotherapy

Hair loss is a chronic process (especially genetic hair loss). Mesotherapy stops hair loss and strengthens the hair, but it does not change the genetic codes. Therefore, to maintain the results obtained, the treatment should not be completely discontinued, but supported with “maintenance sessions”. Refresher doses 2-3 times a year help maintain hair quality for many years.

Mesotherapy as a Supportive Treatment After Hair Transplantation

Applying mesotherapy after hair transplantation operations increases the survival rate of the transplanted roots (grafts). It also accelerates the post-operative healing process, supports repair in the donor area, and strengthens existing hair that was not transplanted, preventing it from falling out. It is generally recommended to start mesotherapy 1 month after transplantation.

Managing Dandruff and Scalp Problems with Hair Mesotherapy

Scalp health directly affects hair quality. Mesotherapy cocktails can be enriched with ingredients that balance sebum production and regulate skin flora. This helps control problems such as stubborn dandruff, excessive oiliness, or dryness, creating a healthy environment for hair follicles.

Hair Mesotherapy Prices and Determining Factors

Mesotherapy prices vary depending on the brand of the product used, the richness of its content (whether it contains peptides, growth factors, etc.), the number of sessions to be applied, and the treatment protocol. A wide variety of mesotherapy products are available on the market; it is essential to use products approved by the Ministry of Health for quality and safety. Due to Ministry of Health regulations, providing price information via the website is not appropriate. For a personalized hair analysis and pricing, it is recommended to contact Izmir Private Demiderm Polyclinic.

Things to Know Before Getting Hair Mesotherapy

Mesotherapy is not a “magic wand,” but a scientific treatment method. Success requires patience, regular participation, and expert physician follow-up. In addition to treatment, paying attention to your diet, avoiding smoking, and using the right hair care products will increase effectiveness. Hair regrowth is not effective in areas where hair follicles are completely dead; hair transplantation is the only solution for these areas.

The content on this page is for informational purposes only. It does not constitute diagnosis or treatment. Hair loss treatments and mesotherapy applications are medical procedures that require individual planning.